Innovative healthcare interventions for non-communicable diseases
Cluster 1 - Health (Two stage - 2027) · HORIZON-RIA · Needs partners
What this call funds
This call funds early-stage clinical trials that test new or improved treatments and disease-management approaches for major non-communicable diseases: cardiovascular disease, diabetes, chronic respiratory disease, and chronic kidney disease. Projects must already have completed lab research, proof-of-concept safety and efficacy work, and a draft clinical trial protocol before applying. The goal is to move promising interventions through phase 1/2 trials while building shared data, engaging patients, and assessing health-economic value for future scale-up.
digital health · pharmaceuticals · public health · medical devices · diagnostics
Who wins this
A clinical research consortium with hospitals, universities, and possibly SMEs that has already completed preclinical work and is ready to launch early-phase clinical trials for one of the four targeted chronic disease areas.
Could you win this call?
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The call in detail
- Indicative grant size
- €7M–€8M
- Funding model
- Lump sum — paid per completed work package, no financial reporting of actual costs
- Submission
- Two-stage submission (short outline first, full proposal if invited)
- Cut-off dates (2)
- 13 Apr 2027 · 22 Sep 2027
- Type of action
- HORIZON Research and Innovation Actions
- Partners
- Required. The call asks for a consortium — a group applying together, typically 3+ organisations from 3+ countries.
- Also required
- Preclinical research and draft clinical trial protocol must be completed and evidence of preliminary consultations with ethics/regulatory authorities provided at submission; only phase 1/2 pharmacological trials or equivalent non-pharmacological interventions are in scope; comparative effectiveness studies and diseases outside the four listed NCDs are excluded.
- Eligible countries (45)
- Austria, Belgium, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Norway, Iceland, Switzerland, United Kingdom, IL, TR, UA, RS, MK, ME, AL, BA, XK, GE, AM, MD, TN, NZ
Read the full conditions from the official call ›
General conditions 1. Admissibility Conditions, proposal page limit and layout Applicants submitting a proposal for a blind evaluation (see General Annex F) must not disclose their organisation names, acronyms, logos nor names of personnel in the proposal abstract and Part B of their first-stage application (see General Annex E). Admissibility conditions are described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes. Proposal page limits and layout are described in Part B of the Application Form available in the Submission System. 2. Eligible Countries Eligible countries are described in Annex B of the Work Programme General Annexes. A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide. 3. Other Eligibility Conditions In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding. If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used). Subject to restrictions for the protection of European communication networks. Other eligibility conditions are described in Annex B of the Work Programme General Annexes. 4. Financial and operational capacity and exclusion Financial and operational capacity and exclusion are described in Annex C of the Work Programme General Annexes. 5a. Evaluation and award: Award criteria, scoring and thresholds The first-stage proposals of this topic will be evaluated blindly. Award criteria, scoring and thresholds are described in Annex D of the Work Programme General Annexes. 5b. Evaluation and award: Submission and evaluation processes For the first stage, the thresholds for each criterion will be 4 (Excellence) and 4 (Impact). The overall threshold applying to the sum of the two individual scores will be set at a level that ensures the total requested budget of proposals admitted to stage 2 is as close as possible to three times the available budget, and not less than two and a half times the available budget. For the second stage, the thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12. Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual. 5c. Evaluation and award: Indicative timeline for evaluation and grant agreement Indicative timeline for evaluation and grant agreement are described in Annex F of the Work Programme General Annexes. 6. Legal and financial set-up of the grants The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5. Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf ]]. Legal and financial set-up of the grants are described in Annex G of the Work Programme General Annexes. Specific conditions Specific conditions are described in the specific topic of the Work Programme. Application and evaluation forms and additional documents: Application and
Who has won calls like this
Organisations that most often win this call family · 44 past winners