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    HORIZON-HLTH-2027-03-TOOL-04

    Virtual Human Twins (VHTs) for integrated clinical decision support in prevention and diagnosis

    Opens 3 Jun 2027Live official EU data

    Cluster 1 - Health (Single stage - 2027/2) · HORIZON-RIA · Needs partners

    22 Sep 2027
    Deadline
    3 Jun 2027
    Opens for applications
    €10M–€12M
    Indicative, per project
    ~4
    Grants expected
    79
    Past winners in this family

    What this call funds

    This call funds research projects that build 'Virtual Human Twin' computer models - detailed digital simulations of a patient's organs and body systems - to help doctors better prevent and diagnose complex diseases. Projects should combine multiple modelling approaches (like AI and biophysics) into working tools that are clinically tested and shown to be cost-effective, then made available on the EU's shared VHT platform. About four projects will share roughly 39 million euros.

    digital health · diagnostics · artificial intelligence · public health · medical devices · research excellence

    Who wins this

    A multidisciplinary consortium of research organisations, hospitals/clinical partners, and technology developers (with SME participation encouraged) capable of building and clinically validating complex multi-organ computational models for disease prevention and diagnosis.

    Could you win this call?

    We read your site to see what you build.

    The call in detail

    Indicative grant size
    €10M–€12M
    Funding model
    Budget-based — reimbursement of actual eligible costs
    Submission
    Single-stage submission (full proposal at once)
    Type of action
    HORIZON Research and Innovation Actions
    Partners
    Required. The call asks for a consortium — a group applying together, typically 3+ organisations from 3+ countries.
    Also required
    Proposals must include clinical studies, contribute to the European VHT Initiative and Platform for Advanced VHT Models (with budget reserved for this), include social sciences and humanities expertise, and any US-established legal entity is eligible for funding due to reciprocal NIH provisions.
    Eligible countries (45)
    Austria, Belgium, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Norway, Iceland, Switzerland, United Kingdom, IL, TR, UA, RS, MK, ME, AL, BA, XK, GE, AM, MD, TN, NZ
    Read the full conditions from the official call ›

    General conditions 1. Admissibility Conditions, proposal page limit and layout Admissibility conditions are  described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes. Proposal page limits and layout are described in Part B of the Application Form available in the Submission System. 2. Eligible Countries Eligible countries are described in Annex B of the Work Programme General Annexes. A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide. 3. Other Eligibility Conditions In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding. If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used). Subject to restrictions for the protection of European communication networks. Other eligibility conditions are described in Annex B of the Work Programme General Annexes. 4. Financial and operational capacity and exclusion Financial and operational capacity and exclusion are described in Annex C of the Work Programme General Annexes. 5a. Evaluation and award: Award criteria, scoring and thresholds Award criteria, scoring and thresholds are described in Annex D of the Work Programme General Annexes. 5b. Evaluation and award: Submission and evaluation processes The thresholds for each criterion will be 4 (Excellence), 4 (Impact) and 4 (Implementation). The cumulative threshold will be 12. Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual. 5c. Evaluation and award: Indicative timeline for evaluation and grant agreement Indicative timeline for evaluation and grant agreement are described in Annex F of the Work Programme General Annexes. 6. Legal and financial set-up of the grants The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5. Legal and financial set-up of the grants are described in Annex G of the Work Programme General Annexes. Specific conditions Specific conditions are described in the specific topic of the Work Programme. Application and evaluation forms and additional documents: Application and

    Who has won calls like this

    Organisations that most often win this call family · 79 past winners

    KATHOLIEKE UNIVERSITEIT LEUVEN · BE
    10 wins
    led 1
    UNIVERSITAIR MEDISCH CENTRUM UTRECHT · NL
    10 wins
    led 2
    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE · FR
    9 wins
    led 2
    ASSISTANCE PUBLIQUE HOPITAUX DE PARIS · FR
    8 wins
    REGION STOCKHOLM · SE
    8 wins
    led 1
    CHARITE - UNIVERSITAETSMEDIZIN BERLIN · DE
    8 wins
    led 1

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